DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C

The integrity of the nuclear envelope (NE) is essential for maintaining the structural stability of the nucleus. Rupture of the NE has been frequently observed in cancer cells, especially in the context of mechanical challenges, such as physical confinement and migration. However, spontaneous NE rup...

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Detalles Bibliográficos
Autores principales: Kovacs, Marton Tibor, Vallette, Marie, Wiertsema, Pauline, Dingli, Florent, Loew, Damarys, Nader, Guilherme Pedreira de Freitas, Piel, Matthieu, Ceccaldi, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597398/
https://www.ncbi.nlm.nih.gov/pubmed/37832547
http://dx.doi.org/10.1016/j.molcel.2023.09.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597398/
https://www.ncbi.nlm.nih.gov/pubmed/37832547
http://dx.doi.org/10.1016/j.molcel.2023.09.023

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