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Cell-intrinsic and -extrinsic effects of SARS-CoV-2 RNA on pathogenesis: single-cell meta-analysis

Single-cell RNA-seq has been used to characterize human COVID-19. To determine if preclinical models successfully mimic the cell-intrinsic and -extrinsic effects of severe disease, we conducted a meta-analysis of single-cell data across five model species. To assess whether dissemination of viral RN...

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Detalles Bibliográficos
Autores principales: Khatun, Mst Shamima, Remcho, T. Parks, Qin, Xuebin, Kolls, Jay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597400/
https://www.ncbi.nlm.nih.gov/pubmed/37737611
http://dx.doi.org/10.1128/msphere.00375-23