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Novel inhibitors that target bacterial virulence identified via HTS against intra-macrophage survival of Shigella flexneri

Shigella flexneri is a facultative intracellular pathogen that causes shigellosis, a human diarrheal disease characterized by the destruction of the colonic epithelium. Novel antimicrobial compounds to treat infections are urgently needed due to the proliferation of bacterial antibiotic resistance a...

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Detalles Bibliográficos
Autores principales: Miljkovic, Marija, Lozano, Sonia, Castellote, Isabel, de Cózar, Cristina, Villegas-Moreno, Ana I., Gamallo, Pablo, Jimenez-Alfaro Martinez, Dolores, Fernández-Álvaro, Elena, Ballell, Lluis, Garcia, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597453/
https://www.ncbi.nlm.nih.gov/pubmed/37565760
http://dx.doi.org/10.1128/msphere.00154-23