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Novel inhibitors that target bacterial virulence identified via HTS against intra-macrophage survival of Shigella flexneri
Shigella flexneri is a facultative intracellular pathogen that causes shigellosis, a human diarrheal disease characterized by the destruction of the colonic epithelium. Novel antimicrobial compounds to treat infections are urgently needed due to the proliferation of bacterial antibiotic resistance a...
Autores principales: | Miljkovic, Marija, Lozano, Sonia, Castellote, Isabel, de Cózar, Cristina, Villegas-Moreno, Ana I., Gamallo, Pablo, Jimenez-Alfaro Martinez, Dolores, Fernández-Álvaro, Elena, Ballell, Lluis, Garcia, George A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597453/ https://www.ncbi.nlm.nih.gov/pubmed/37565760 http://dx.doi.org/10.1128/msphere.00154-23 |
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