Reconstitution of a minimal ESX-5 type VII secretion system suggests a role for PPE proteins in the outer membrane transport of proteins

Mycobacteria utilize type VII secretion systems (T7SSs) to secrete proteins across their highly hydrophobic and diderm cell envelope. Pathogenic mycobacteria have up to five different T7SSs, called ESX-1 to ESX-5, which are crucial for growth and virulence. Here, we use a functionally reconstituted...

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Detalles Bibliográficos
Autores principales: Bunduc, C. M., Ding, Y., Kuijl, C., Marlovits, T. C., Bitter, W., Houben, E. N. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597459/
https://www.ncbi.nlm.nih.gov/pubmed/37747201
http://dx.doi.org/10.1128/msphere.00402-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597459/
https://www.ncbi.nlm.nih.gov/pubmed/37747201
http://dx.doi.org/10.1128/msphere.00402-23

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