Vaborbactam increases meropenem susceptibility in Pseudomonas aeruginosa clinical isolates displaying MexXY and AmpC upregulation

To evaluate the resistance mechanisms among Pseudomonas aeruginosa clinical isolates exhibiting meropenem (MEM) MIC values higher than meropenem-vaborbactam (MEV). P. aeruginosa clinical isolates collected in US hospitals from 2014 to 2019 were susceptibility tested. Whole-genome and transcriptome s...

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Detalles Bibliográficos
Autores principales: Castanheira, Mariana, Doyle, Timothy B., Hubler, Cory M., DeVries, Sean, Shortridge, Dee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597463/
https://www.ncbi.nlm.nih.gov/pubmed/37768064
http://dx.doi.org/10.1128/msphere.00162-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597463/
https://www.ncbi.nlm.nih.gov/pubmed/37768064
http://dx.doi.org/10.1128/msphere.00162-23

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