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USP7 attenuates endoplasmic reticulum stress-induced apoptotic cell death through deubiquitination and stabilization of FBXO7

Parkinson’s disease (PD) is a common neurodegenerative disease (NDD) characterized by the loss of dopaminergic neurons in the substantia nigra. Similar to other NDDs, the buildup of toxic protein aggregates in PD leads to progressive neuronal loss, culminating in neurodegeneration. Accumulating evid...

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Detalles Bibliográficos
Autores principales: Lee, Su Hyoun, Chung, Kwang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597484/
https://www.ncbi.nlm.nih.gov/pubmed/37874827
http://dx.doi.org/10.1371/journal.pone.0290371