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Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer’s disease

Blood-brain barrier (BBB) dysfunction may be involved in the increased sensitivity of Alzheimer’s disease (AD) patients to antipsychotics, including amisulpride. Studies indicate that antipsychotics interact with facilitated glucose transporters (GLUT), including GLUT1, and that GLUT1 BBB expression...

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Detalles Bibliográficos
Autores principales: Boyanova, Sevda T., Lloyd-Morris, Ethlyn, Corpe, Christopher, Rahman, Khondaker Miraz, Farag, Doaa B., Page, Lee K., Wang, Hao, Fleckney, Alice L., Gatt, Ariana, Troakes, Claire, Vizcay-Barrena, Gema, Fleck, Roland, Reeves, Suzanne J., Thomas, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597500/
https://www.ncbi.nlm.nih.gov/pubmed/37874822
http://dx.doi.org/10.1371/journal.pone.0286278