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Assessing the performance of methods for cell clustering from single-cell DNA sequencing data

BACKGROUND: Many cancer genomes have been known to contain more than one subclone inside one tumor, the phenomenon of which is called intra-tumor heterogeneity (ITH). Characterizing ITH is essential in designing treatment plans, prognosis as well as the study of cancer progression. Single-cell DNA s...

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Detalles Bibliográficos
Autores principales: Khan, Rituparna, Mallory, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597505/
https://www.ncbi.nlm.nih.gov/pubmed/37824596
http://dx.doi.org/10.1371/journal.pcbi.1010480