An ex vivo rat trachea model reveals abnormal airway physiology and a gland secretion defect in cystic fibrosis

Cystic fibrosis (CF) is a genetic disease hallmarked by aberrant ion transport that results in delayed mucus clearance, chronic infection, and progressive lung function decline. Several animal models have been developed to study the airway anatomy and mucus physiology in CF, but they are costly and...

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Detalles Bibliográficos
Autores principales: Harris, Elex, Easter, Molly, Ren, Janna, Krick, Stefanie, Barnes, Jarrod, Rowe, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597513/
https://www.ncbi.nlm.nih.gov/pubmed/37874846
http://dx.doi.org/10.1371/journal.pone.0293367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597513/
https://www.ncbi.nlm.nih.gov/pubmed/37874846
http://dx.doi.org/10.1371/journal.pone.0293367

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