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An ex vivo rat trachea model reveals abnormal airway physiology and a gland secretion defect in cystic fibrosis
Cystic fibrosis (CF) is a genetic disease hallmarked by aberrant ion transport that results in delayed mucus clearance, chronic infection, and progressive lung function decline. Several animal models have been developed to study the airway anatomy and mucus physiology in CF, but they are costly and...
Autores principales: | Harris, Elex, Easter, Molly, Ren, Janna, Krick, Stefanie, Barnes, Jarrod, Rowe, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597513/ https://www.ncbi.nlm.nih.gov/pubmed/37874846 http://dx.doi.org/10.1371/journal.pone.0293367 |
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