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The nexus of dynamic T cell states and immune checkpoint blockade therapy in the periphery and tumor microenvironment
Immune checkpoint blockade (ICB) therapies, that is, using monoclonal antibodies to reinvigorate tumor-reactive, antigen-specific T cells from the inhibitory effects of CTLA-4, PD-1 and PD-L1 immune checkpoints, have revolutionized the therapeutic landscape of modern oncology. However, only a subset...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597640/ https://www.ncbi.nlm.nih.gov/pubmed/37881432 http://dx.doi.org/10.3389/fimmu.2023.1267918 |