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Effect of Astragali radix extract on pharmacokinetic behavior of dapagliflozin in healthy and type 2 diabetic rats

Objective: This study aimed to investigate effect of antidiabetic herb Astragali Radix (AR) on pharmacokinetic behavior of dapagliflozin (DAPA) in healthy rats and type 2 diabetes mellitus (T2DM) rats. Methods: The T2DM rats were induced by high-fat diet (HFD) and intraperitoneal injection of strept...

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Detalles Bibliográficos
Autores principales: Du, Wandi, Hu, Jiarong, Liang, Jingru, Yang, Xiaolei, Fang, Boyu, Ma, Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597649/
https://www.ncbi.nlm.nih.gov/pubmed/37881186
http://dx.doi.org/10.3389/fphar.2023.1214658