DNA damage and repair: underlying mechanisms leading to microcephaly

DNA-damaging agents and endogenous DNA damage constantly harm genome integrity. Under genotoxic stress conditions, the DNA damage response (DDR) machinery is crucial in repairing lesions and preventing mutations in the basic structure of the DNA. Different repair pathways are implicated in the resol...

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Detalles Bibliográficos
Autores principales: Ribeiro, Jessica Honorato, Altinisik, Nazlican, Rajan, Nicholas, Verslegers, Mieke, Baatout, Sarah, Gopalakrishnan, Jay, Quintens, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597653/
https://www.ncbi.nlm.nih.gov/pubmed/37881689
http://dx.doi.org/10.3389/fcell.2023.1268565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597653/
https://www.ncbi.nlm.nih.gov/pubmed/37881689
http://dx.doi.org/10.3389/fcell.2023.1268565

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