Formyl-peptide receptor 2 signalling triggers aerobic metabolism of glucose through Nox2-dependent modulation of pyruvate dehydrogenase activity

The human formyl-peptide receptor 2 (FPR2) is activated by an array of ligands. By phospho-proteomic analysis we proved that FPR2 stimulation induces redox-regulated phosphorylation of many proteins involved in cellular metabolic processes. In this study, we investigated metabolic pathways activated...

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Detalles Bibliográficos
Autores principales: Cimmino, Tiziana Pecchillo, Pagano, Ester, Stornaiuolo, Mariano, Esposito, Gabriella, Ammendola, Rosario, Cattaneo, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597678/
https://www.ncbi.nlm.nih.gov/pubmed/37875162
http://dx.doi.org/10.1098/rsob.230336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597678/
https://www.ncbi.nlm.nih.gov/pubmed/37875162
http://dx.doi.org/10.1098/rsob.230336

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