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Formyl-peptide receptor 2 signalling triggers aerobic metabolism of glucose through Nox2-dependent modulation of pyruvate dehydrogenase activity
The human formyl-peptide receptor 2 (FPR2) is activated by an array of ligands. By phospho-proteomic analysis we proved that FPR2 stimulation induces redox-regulated phosphorylation of many proteins involved in cellular metabolic processes. In this study, we investigated metabolic pathways activated...
Autores principales: | Cimmino, Tiziana Pecchillo, Pagano, Ester, Stornaiuolo, Mariano, Esposito, Gabriella, Ammendola, Rosario, Cattaneo, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597678/ https://www.ncbi.nlm.nih.gov/pubmed/37875162 http://dx.doi.org/10.1098/rsob.230336 |
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