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Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation correlating with increasing fatigue severity

BACKGROUND: Many patients with SARS-CoV-2 infection develop long COVID with fatigue as one of the most disabling symptoms. We performed clinical and immune profiling of fatigued and non-fatigued long COVID patients and age- and sex-matched healthy controls (HCs). METHODS: Long COVID symptoms were as...

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Detalles Bibliográficos
Autores principales: Berentschot, Julia C., Drexhage, Hemmo A., Aynekulu Mersha, Daniel G., Wijkhuijs, Annemarie J. M., GeurtsvanKessel, Corine H., Koopmans, Marion P. G., Voermans, Jolanda J. C., Hendriks, Rudi W., Nagtzaam, Nicole M. A., de Bie, Maaike, Heijenbrok-Kal, Majanka H., Bek, L. Martine, Ribbers, Gerard M., van den Berg-Emons, Rita J. G., Aerts, Joachim G. J. V., Dik, Willem A., Hellemons, Merel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597688/
https://www.ncbi.nlm.nih.gov/pubmed/37881427
http://dx.doi.org/10.3389/fimmu.2023.1254899