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AGEs induce high expression of Dll4 via endoplasmic reticulum stress PERK signaling-mediated internal ribosomal entry site mechanism in macrophages

BACKGROUND AND AIM: Advanced glycation end products (AGEs)- exposed macrophages was characterized by Delta-like ligand 4 (Dll4) high expressed and has been shown to participate in diabetes-related atherosclerosis. This study was aimed to investigate the translational regulatory mechanism of Dll4 hig...

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Detalles Bibliográficos
Autores principales: Ma, Yanpeng, Zheng, Shixiang, Wang, Xiqiang, Zhu, Ling, Wang, Junkui, Pan, Shuo, Zhang, Yong, Liu, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597754/
https://www.ncbi.nlm.nih.gov/pubmed/37886757
http://dx.doi.org/10.1016/j.heliyon.2023.e21170