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Clinical consequences of a genetic predisposition toward higher benign prostate-specific antigen levels

BACKGROUND: Prostate-specific antigen (PSA) levels are influenced by genetic variation unrelated to prostate cancer risk. Whether a genetic predisposition to a higher PSA level predisposes to a diagnostic work-up for prostate cancer is not known. METHODS: Participants were 3110 men of African and Eu...

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Detalles Bibliográficos
Autores principales: Shi, Mingjian, Shelley, John P., Schaffer, Kerry R., Tosoian, Jeffrey J., Bagheri, Minoo, Witte, John S., Kachuri, Linda, Mosley, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597757/
https://www.ncbi.nlm.nih.gov/pubmed/37865044
http://dx.doi.org/10.1016/j.ebiom.2023.104838