Non-canonical amino acid incorporation into AAV5 capsid enhances lung transduction in mice

Gene therapy using recombinant adeno-associated virus (rAAV) relies on safe, efficient, and precise in vivo gene delivery that is largely dependent on the AAV capsid. The proteinaceous capsid is highly amenable to engineering using a variety of approaches, and most resulting capsids carry substituti...

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Detalles Bibliográficos
Autores principales: Chang, Hao, Du, Ailing, Jiang, Jun, Ren, Lingzhi, Liu, Nan, Zhou, Xuntao, Liang, Jialing, Gao, Guangping, Wang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597788/
https://www.ncbi.nlm.nih.gov/pubmed/37886602
http://dx.doi.org/10.1016/j.omtm.2023.101129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597788/
https://www.ncbi.nlm.nih.gov/pubmed/37886602
http://dx.doi.org/10.1016/j.omtm.2023.101129

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