Cargando…

Design, synthesis and anticancer evaluation of polymethoxy aurones as potential cell cycle inhibitors

BACKGROUND: Cancer is the most fatal disease in humans and the aberrant activity of various cell cycle proteins results in uncontrolled tumor cell proliferation, thus, regulating the cell cycle is an attractive target in cancer therapy. OBJECTIVES: Aurone is a naturally occurring active compound wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Zheng, Han, Yaoyao, Li, Xiaolan, Zhang, Qiuping, Deng, Renjin, Ren, Hong, He, Wenjing, Wu, Xinduo, Guo, Hongwei, Zhu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597867/
https://www.ncbi.nlm.nih.gov/pubmed/37886750
http://dx.doi.org/10.1016/j.heliyon.2023.e21054