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Nucleophosmin 1 cooperates with BRD4 to facilitate c-Myc transcription to promote prostate cancer progression

Nucleophosmin 1 (NPM1) is a multifunctional protein that promotes tumor progression in various cancers and is associated with a poor prognosis of prostate cancer (PCa). However, the mechanism by which NPM1 exerts its malignant potential in PCa remains elusive. Here, we showed that NPM1 is overexpres...

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Detalles Bibliográficos
Autores principales: Hong, Zhe, Xu, Chengdang, Zheng, Shengfeng, Wang, Xinan, Tao, Yiran, Tan, Yao, Lin, Guowen, Wu, Denglong, Ye, Dingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597990/
https://www.ncbi.nlm.nih.gov/pubmed/37875480
http://dx.doi.org/10.1038/s41420-023-01682-w