Characteristics of premanufacture CD8(+) T cells determine CAR-T efficacy in patients with diffuse large B-cell lymphoma

Although chimeric antigen receptor (CAR) T cells have become an important treatment option for patients with relapsed/refractory B-cell malignancies, more than 60% of patients with diffuse large B-cell lymphoma (DLBCL) treated with CAR-T cell therapies fail to achieve a durable response. To reveal c...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Tong, Chuan, Lu, Yuting, Wu, Zhiqiang, Guo, Yelei, Liu, Yang, Wei, Jianshu, Wang, Chunmeng, Yang, Qingming, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598004/
https://www.ncbi.nlm.nih.gov/pubmed/37875502
http://dx.doi.org/10.1038/s41392-023-01659-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598004/
https://www.ncbi.nlm.nih.gov/pubmed/37875502
http://dx.doi.org/10.1038/s41392-023-01659-2

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