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Population pharmacokinetic modeling of multiple-dose intravenous fosfomycin in critically ill patients during continuous venovenous hemodialysis

The aim of this study was to investigate the pharmacokinetics of multiple-dose intravenous (i.v.) fosfomycin in critically ill patients during continuous venovenous hemodialysis (CVVHD). Non-compartmental analysis and population pharmacokinetic modeling were used to simulate different dosing regimen...

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Detalles Bibliográficos
Autores principales: Hüppe, Tobias, Götz, Katharina M., Meiser, Andreas, de Faria Fernandes, Andrea, Maurer, Felix, Groesdonk, Heinrich V., Volk, Thomas, Lehr, Thorsten, Kreuer, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598009/
https://www.ncbi.nlm.nih.gov/pubmed/37875513
http://dx.doi.org/10.1038/s41598-023-45084-5