Sohlh2 promotes pulmonary fibrosis via repression of p62/Keap1/Nrf2 mediated anti-oxidative signaling pathway

Disturbance in the redox balance of alveolar epithelial cells (AECs) was considered as a causal factor for pulmonary fibrosis. The regulatory mechanisms of redox hemostasis in the development of pulmonary fibrosis remain largely unknown. Using a type II AEC-specific Sohlh2 conditional knock-in (CKI)...

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Detalles Bibliográficos
Autores principales: Liu, Lanlan, Zhang, Xiaoli, Zhang, Ruihong, Wang, Liyan, Zhi, Sujuan, Feng, Xiaoning, Liu, Xuyue, Shen, Ying, Hao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598036/
https://www.ncbi.nlm.nih.gov/pubmed/37875506
http://dx.doi.org/10.1038/s41419-023-06179-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598036/
https://www.ncbi.nlm.nih.gov/pubmed/37875506
http://dx.doi.org/10.1038/s41419-023-06179-z

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