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Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells

The disease progression of the metabolic syndrome is associated with prolonged hyperlipidemia and insulin resistance, eventually giving rise to impaired insulin secretion, often concomitant with hypoadiponectinemia. As an adipose tissue derived hormone, adiponectin is beneficial for insulin secretio...

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Detalles Bibliográficos
Autores principales: Onodera, Toshiharu, Kim, Dae-Seok, Ye, Risheng, Wang, May-Yun, Chen, Shiuhwei, Field, Bianca C., Straub, Leon, Sun, Xue-Nan, Li, Chao, Lee, Charlotte, Paredes, Megan, Crewe, Clair, Zhao, Shangang, Kusminski, Christine M., Gordillo, Ruth, Scherer, Philipp E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598053/
https://www.ncbi.nlm.nih.gov/pubmed/37806486
http://dx.doi.org/10.1016/j.molmet.2023.101821