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FOXQ1 promotes pancreatic cancer cell proliferation, tumor stemness, invasion and metastasis through regulation of LDHA-mediated aerobic glycolysis

Pancreatic cancer (PC), a gastrointestinal tract malignant tumor, has a poor prognosis due to early metastasis and limited response to chemotherapy. Therefore, identifying novel therapeutic approaches for PC is critical. Epithelial–mesenchymal transition (EMT) is known as the vital progress in PC de...

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Detalles Bibliográficos
Autores principales: Wu, Changhao, Zheng, Chenglong, Chen, Shiyu, He, Zhiwei, Hua, Hao, Sun, Chengyi, Yu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598070/
https://www.ncbi.nlm.nih.gov/pubmed/37875474
http://dx.doi.org/10.1038/s41419-023-06207-y