In vivo Assessment of the Impact of Molecular Weight on Constructs of (68)Ga-DOTA-Manocept in a Syngeneic Mouse Tumor Model

PURPOSE: Manocept™ constructs are mannosylated amine dextrans (MADs) that bind with high affinity to the mannose receptor, CD206. Tumor-associated macrophages (TAMs) are the most numerous immune cells in the tumor microenvironment and a recognized target for tumor imaging and cancer immunotherapies....

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Detalles Bibliográficos
Autores principales: Bartels, Jennifer L., Fernandez, Solana R., Arnold, Jeffrey S., Parker, Candace C., Tekin, Volkan, O’Malley, Grace, Ralph, David A., Lapi, Suzanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598080/
https://www.ncbi.nlm.nih.gov/pubmed/36882605
http://dx.doi.org/10.1007/s11307-023-01809-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598080/
https://www.ncbi.nlm.nih.gov/pubmed/36882605
http://dx.doi.org/10.1007/s11307-023-01809-6

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