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Ectopic expression of human TUBB8 leads to increased aneuploidy in mouse oocytes

Aneuploidy seriously compromises female fertility and increases incidence of birth defects. Rates of aneuploidy in human eggs from even young women are significantly higher than those in other mammals. However, intrinsic genetic factors underlying this high incidence of aneuploidy in human eggs rema...

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Detalles Bibliográficos
Autores principales: Dong, Jie, Jin, Liping, Bao, Shihua, Chen, Biaobang, Zeng, Yang, Luo, Yuxi, Du, Xingzhu, Sang, Qing, Wu, Tianyu, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598138/
https://www.ncbi.nlm.nih.gov/pubmed/37875488
http://dx.doi.org/10.1038/s41421-023-00599-z