Identification of ONECUT3 as a stemness-related transcription factor regulating NK cell-mediated immune evasion in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) has a dismal response to the current T cell-based immunotherapies, which is attributed to intratumoral heterogeneity caused by PDAC stem cells and lack of major histocompatibility complex class I required for neoantigen presentation. Although this scenario mak...

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Detalles Bibliográficos
Autores principales: Shi, Haojun, Tsang, Yiusing, Yang, Yisi, Chin, Hok Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598193/
https://www.ncbi.nlm.nih.gov/pubmed/37875589
http://dx.doi.org/10.1038/s41598-023-45560-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598193/
https://www.ncbi.nlm.nih.gov/pubmed/37875589
http://dx.doi.org/10.1038/s41598-023-45560-y

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