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Biomimetic nanovaccine-mediated multivalent IL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy

Cytokine therapy, involving interleukin-15 (IL-15), is a promising strategy for cancer immunotherapy. However, clinical application has been limited due to severe toxicity and the relatively low immune response rate, caused by wide distribution of cytokine receptors, systemic immune activation and s...

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Detalles Bibliográficos
Autores principales: Wang, Kaiyuan, Zhang, Xuanbo, Ye, Hao, Wang, Xia, Fan, Zhijin, Lu, Qi, Li, Songhao, Zhao, Jian, Zheng, Shunzhe, He, Zhonggui, Ni, Qianqian, Chen, Xiaoyuan, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598200/
https://www.ncbi.nlm.nih.gov/pubmed/37875481
http://dx.doi.org/10.1038/s41467-023-42155-z