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Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase

Biomolecular polyelectrolyte complexes can be formed between oppositely charged intrinsically disordered regions (IDRs) of proteins or between IDRs and nucleic acids. Highly charged IDRs are abundant in the nucleus, yet few have been functionally characterized. Here, we show that a positively charge...

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Detalles Bibliográficos
Autores principales: Papageorgiou, Anna C., Pospisilova, Michaela, Cibulka, Jakub, Ashraf, Raghib, Waudby, Christopher A., Kadeřávek, Pavel, Maroz, Volha, Kubicek, Karel, Prokop, Zbynek, Krejci, Lumir, Tripsianes, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598209/
https://www.ncbi.nlm.nih.gov/pubmed/37875529
http://dx.doi.org/10.1038/s41467-023-42503-z