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Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase
Biomolecular polyelectrolyte complexes can be formed between oppositely charged intrinsically disordered regions (IDRs) of proteins or between IDRs and nucleic acids. Highly charged IDRs are abundant in the nucleus, yet few have been functionally characterized. Here, we show that a positively charge...
Autores principales: | Papageorgiou, Anna C., Pospisilova, Michaela, Cibulka, Jakub, Ashraf, Raghib, Waudby, Christopher A., Kadeřávek, Pavel, Maroz, Volha, Kubicek, Karel, Prokop, Zbynek, Krejci, Lumir, Tripsianes, Konstantinos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598209/ https://www.ncbi.nlm.nih.gov/pubmed/37875529 http://dx.doi.org/10.1038/s41467-023-42503-z |
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