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Dual RNA-seq to catalogue host and parasite gene expression changes associated with virulence of T. annulata-transformed bovine leukocytes: towards identification of attenuation biomarkers

The apicomplexan parasite Theileria annulata is transmitted by Hyalomma ticks and causes an acute lymphoproliferative disease that is invariably lethal in exotic cattle breeds. The unique ability of the schizont stage of T. annulata to transform infected leukocytes to a cancer-like phenotype and the...

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Detalles Bibliográficos
Autores principales: Elati, Khawla, Tajeri, Shahin, Obara, Isaiah, Mhadhbi, Moez, Zweygarth, Erich, Darghouth, Mohamed Aziz, Nijhof, Ard Menzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598219/
https://www.ncbi.nlm.nih.gov/pubmed/37875584
http://dx.doi.org/10.1038/s41598-023-45458-9