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DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation

Emerging evidence indicates that DNA methylation plays an important role in the initiation and progression of nasopharyngeal carcinoma (NPC). DNAJA4 is hypermethylated in NPC, while its role in regulating NPC progression remains unclear. Here, we revealed that the promoter of DNAJA4 was hypermethyla...

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Detalles Bibliográficos
Autores principales: Zhang, Qun, Feng, Ping, Zhu, Xun-Hua, Zhou, Shi-Qing, Ye, Ming-Liang, Yang, Xiao-Jing, Gong, Sha, Huang, Sheng-Yan, Tan, Xi-Rong, He, Shi-Wei, Li, Ying-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598267/
https://www.ncbi.nlm.nih.gov/pubmed/37875476
http://dx.doi.org/10.1038/s41419-023-06225-w