Predicted resistance to broadly neutralizing antibodies (bnAbs) and associated HIV-1 envelope characteristics among seroconverting adults in Botswana

We used HIV-1C sequences to predict (in silico) resistance to 33 known broadly neutralizing antibodies (bnAbs) and evaluate the different HIV-1 Env characteristics that may affect virus neutralization. We analyzed proviral sequences from adults with documented HIV-1 seroconversion (N = 140) in Botsw...

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Detalles Bibliográficos
Autores principales: Moraka, Natasha O., Choga, Wonderful T., Pema, Marea N., Chawawa, Moses Kudzai, Gobe, Irene, Mokomane, Margaret, Bareng, Ontlametse T., Bhebhe, Lynette, Kelentse, Nametso, Mulenga, Graceful, Pretorius Holme, Molly, Mohammed, Terence, Koofhethile, Catherine K., Makhema, Joseph M., Shapiro, Roger, Lockman, Shahin, Moyo, Sikhulile, Gaseitsiwe, Simani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598268/
https://www.ncbi.nlm.nih.gov/pubmed/37875518
http://dx.doi.org/10.1038/s41598-023-44722-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598268/
https://www.ncbi.nlm.nih.gov/pubmed/37875518
http://dx.doi.org/10.1038/s41598-023-44722-2

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