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Predicted resistance to broadly neutralizing antibodies (bnAbs) and associated HIV-1 envelope characteristics among seroconverting adults in Botswana
We used HIV-1C sequences to predict (in silico) resistance to 33 known broadly neutralizing antibodies (bnAbs) and evaluate the different HIV-1 Env characteristics that may affect virus neutralization. We analyzed proviral sequences from adults with documented HIV-1 seroconversion (N = 140) in Botsw...
Autores principales: | Moraka, Natasha O., Choga, Wonderful T., Pema, Marea N., Chawawa, Moses Kudzai, Gobe, Irene, Mokomane, Margaret, Bareng, Ontlametse T., Bhebhe, Lynette, Kelentse, Nametso, Mulenga, Graceful, Pretorius Holme, Molly, Mohammed, Terence, Koofhethile, Catherine K., Makhema, Joseph M., Shapiro, Roger, Lockman, Shahin, Moyo, Sikhulile, Gaseitsiwe, Simani |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598268/ https://www.ncbi.nlm.nih.gov/pubmed/37875518 http://dx.doi.org/10.1038/s41598-023-44722-2 |
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