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3', 4'-dihydroxyflavone ameliorates paclitaxel model of peripheral neuropathy in mice by modulating K(ATP) channel, adenosine (A(3)) and GABA(A) (α(2) subunit) receptors

Paclitaxel is a widely used cancer chemotherapeutic agent for many solid tumors; but peripheral neuropathy is a major limitation for its clinical use. Studies have demonstrated the usefulness of flavone derivatives in chemotherapy induced peripheral neuropathy. The present study evaluates the anti-n...

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Detalles Bibliográficos
Autores principales: Ramasamy, Kavitha, Shanmugasundaram, Jaikumar, Subramanian, Viswanathan, Manoharan, Rajesh, Kathirvelu, Parimala, Vijayaraghavan, Rajagopalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598353/
https://www.ncbi.nlm.nih.gov/pubmed/37885774
http://dx.doi.org/10.6026/97320630019754