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Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons
Cytochrome c oxidase (CcO) reduces O(2) in the O(2)-reduction site by sequential four-electron donations through the low-potential metal sites (Cu(A) and Fe(a)). Redox-coupled X-ray crystal structural changes have been identified at five distinct sites including Asp(51), Arg(438), Glu(198), the hydr...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598403/ https://www.ncbi.nlm.nih.gov/pubmed/37742916 http://dx.doi.org/10.1016/j.jbc.2023.105277 |