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miR-431 secreted by human vestibular schwannomas increases the mammalian inner ear’s vulnerability to noise trauma

INTRODUCTION: Vestibular schwannoma (VS) is an intracranial tumor that arises on the vestibular branch of cranial nerve VIII and typically presents with sensorineural hearing loss (SNHL). The mechanisms of this SNHL are postulated to involve alterations in the inner ear’s microenvironment mediated b...

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Detalles Bibliográficos
Autores principales: Fujita, Takeshi, Seist, Richard, Kao, Shyan-Yuan, Soares, Vitor, Panano, Lorena, Khetani, Radhika S., Landegger, Lukas D., Batts, Shelley, Stankovic, Konstantina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598552/
https://www.ncbi.nlm.nih.gov/pubmed/37885485
http://dx.doi.org/10.3389/fneur.2023.1268359