DNA Framework Programmed Conformational Reconstruction of Antibody Complementary Determining Region

[Image: see text] The conformation of complementary determining region (CDR) is crucial in dictating its specificity and affinity for binding with an antigen, making it a focal point in artificial antibody engineering. Although desirable, programmable scaffolds that can regulate the conformation of...

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Detalles Bibliográficos
Autores principales: Zhou, Liqi, Ren, Lei, Bai, Zhiang, Xia, Qinglin, Wang, Yue, Peng, Hongzhen, Yan, Qinglong, Shi, Jiye, Li, Bin, Guo, Linjie, Wang, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598557/
https://www.ncbi.nlm.nih.gov/pubmed/37885585
http://dx.doi.org/10.1021/jacsau.3c00492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598557/
https://www.ncbi.nlm.nih.gov/pubmed/37885585
http://dx.doi.org/10.1021/jacsau.3c00492

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