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Predicting synergistic anticancer drug combination based on low-rank global attention mechanism and bilinear predictor

MOTIVATION: Drug combination therapy has exhibited remarkable therapeutic efficacy and has gradually become a promising clinical treatment strategy of complex diseases such as cancers. As the related databases keep expanding, computational methods based on deep learning model have become powerful to...

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Detalles Bibliográficos
Autores principales: Gan, Yanglan, Huang, Xingyu, Guo, Wenjing, Yan, Cairong, Zou, Guobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598574/
https://www.ncbi.nlm.nih.gov/pubmed/37812255
http://dx.doi.org/10.1093/bioinformatics/btad607