Cargando…

Structural insights into Rad18 targeting by the SLF1 BRCT domains

Rad18 interacts with the SMC5/6 localization factor 1 (SLF1) to recruit the SMC5/6 complex to DNA damage sites for repair. The mechanism of the specific Rad18 recognition by SLF1 is unclear. Here, we present the crystal structure of the tandem BRCT repeat (tBRCT) in SLF1 (SLF1(tBRCT)) bound with the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Wei, Qiu, Fangjie, Zheng, Lin, Shi, Meng, Shen, Miaomiao, Zhao, Xiaolan, Xiang, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598736/ https://www.ncbi.nlm.nih.gov/pubmed/37748650 http://dx.doi.org/10.1016/j.jbc.2023.105288

Ejemplares similares

Structural studies of the PARP-1 BRCT domain
por: Loeffler, Paul A, et al.
Publicado: (2011)

Propagation of SLF/ELF electromagnetic waves
por: Pan, Weiyan, et al.
Publicado: (2014)

BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands
por: Day, Matthew, et al.
Publicado: (2018)

The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion
por: Paddock, Marcia N., et al.
Publicado: (2010)

Functional Evolution of BRCT Domains from Binding DNA to Protein
por: Sheng, Zi-Zhang, et al.
Publicado: (2011)

Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites
por: Wu, Qian, et al.
Publicado: (2016)

Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition
por: Coquelle, Nicolas, et al.
Publicado: (2011)

Correction: The BRCT Domain of PARP-1 Is Required for Immunoglobulin Gene Conversion
por: Paddock, Marcia N., et al.
Publicado: (2018)

Megadalton-node assembly by binding of Skb1 to the membrane anchor Slf1
por: Deng, Lin, et al.
Publicado: (2014)

BRCT Domains: Structure, Functions, and Implications in Disease—New Therapeutic Targets for Innovative Drug Discovery against Infections
por: Peña-Guerrero, José, et al.
Publicado: (2023)

The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis
por: Jansen, Jacob G., et al.
Publicado: (2005)

The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response
por: Li, Mo, et al.
Publicado: (2013)

Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50
por: Choudhary, Rajan Kumar, et al.
Publicado: (2017)

Targeting Phosphopeptide Recognition by the Human BRCA1 Tandem BRCT Domain to Interrupt BRCA1-Dependent Signaling
por: Periasamy, Jayaprakash, et al.
Publicado: (2018)

Discovery and Validation of Lmj_04_BRCT Domain, a Novel Therapeutic Target: Identification of Candidate Drugs for Leishmaniasis
por: Peña-Guerrero, José, et al.
Publicado: (2021)

The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRNA processing
por: Hölzel, Michael, et al.
Publicado: (2007)

Effects on human transcriptome of mutated BRCA1 BRCT domain: A microarray study
por: Iofrida, Caterina, et al.
Publicado: (2012)

Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif
por: Wu, Qian, et al.
Publicado: (2015)

Phosphopeptide interactions of the Nbs1 N-terminal FHA-BRCT1/2 domains
por: Kim, Kyungmin, et al.
Publicado: (2021)

The N-terminal BRCT domain determines MCPH1 function in brain development and fertility
por: Liu, Xiaoqian, et al.
Publicado: (2021)

Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1
por: Ross, Anna-Laura, et al.
Publicado: (2005)

Biophysical evaluation to categorize pathogenicity of cancer-predisposing mutations identified in the BARD1 BRCT domain
por: Choudhary, Rajan Kumar, et al.
Publicado: (2018)

Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy
por: Grange, Laura J., et al.
Publicado: (2022)

Actionable loss of SLF2 drives B‐cell lymphomagenesis and impairs the DNA damage response
por: Zhang, Le, et al.
Publicado: (2023)

Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage
por: Munoz, Ivan M., et al.
Publicado: (2007)

Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage
por: Munoz, Ivan M., et al.
Publicado: (2017)

Analysis of BRCT5 domain-containing proteins reveals a new component of DNA damage repair in Arabidopsis
por: Vladejić, Jovanka, et al.
Publicado: (2022)

Role of BRCT motif containing proteins in Chk1 activation
por: Beniston, RG, et al.
Publicado: (2006)

An atypical BRCT–BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex
por: Hammel, Michal, et al.
Publicado: (2020)

Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification
por: Notenboom, Valerie, et al.
Publicado: (2007)

Structural basis for the Rad6 activation by the Bre1 N-terminal domain
por: Shi, Meng, et al.
Publicado: (2023)

p38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage
por: de Sousa, Mirta Mittelstedt Leal, et al.
Publicado: (2017)

Mutations in the BRCT binding site of BRCA1 result in hyper-recombination
por: Dever, Seth M., et al.
Publicado: (2011)

The importance of simulated lung fluid (SLF) extractions for a more relevant evaluation of the oxidative potential of particulate matter
por: Calas, Aude, et al.
Publicado: (2017)

The tomato 2-oxoglutarate-dependent dioxygenase gene SlF3HL is critical for chilling stress tolerance
por: Hu, Tixu, et al.
Publicado: (2019)

SCF(SLF)-mediated cytosolic degradation of S-RNase is required for cross-pollen compatibility in S-RNase-based self-incompatibility in Petunia hybrida
por: Liu, Wei, et al.
Publicado: (2014)

In Silico and Structure-Based Assessment of Similar Variants Discovered in Tandem Repeats of BRCT Domains of BRCA1 and BARD1 To Characterize the Folding Pattern
por: Barua, Siddhartha A., et al.
Publicado: (2022)

Structure/function studies of the NAD(+)-dependent DNA ligase from the poly-extremophile Deinococcus radiodurans reveal importance of the BRCT domain for DNA binding
por: Fernandes, Andreia, et al.
Publicado: (2023)

Editor's note to ‘phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage’
Publicado: (2022)

The Yeast La Related Protein Slf1p Is a Key Activator of Translation during the Oxidative Stress Response
por: Kershaw, Christopher J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mrdr2f6r81c96vncq14hnsoed5