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Peroxiredoxin 1 alleviates oxygen-glucose deprivation/ reoxygenation injury in N2a cells via suppressing the JNK/caspase-3 pathway

OBJECTIVE(S): Cerebral ischemia/reperfusion (I/R) injury inevitably aggravates the initial cerebral tissue damage following a stroke. Peroxiredoxin 1 (Prdx1) is a representative protein of the endogenous antioxidant enzyme family that regulates several reactive oxygen species (ROS)-dependent signali...

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Detalles Bibliográficos
Autores principales: Yuan, Yang, Tan, Hongchen, Chen, Huailong, Zhang, Jiawen, Shi, Fei, Wang, Mingshan, Zhang, Gaofeng, Wang, Haipeng, Dong, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598809/
https://www.ncbi.nlm.nih.gov/pubmed/37886002
http://dx.doi.org/10.22038/IJBMS.2023.71390.15528