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Irbesartan ameliorates inflammation via transendothelial leukocyte migration due to VCAM-1/NOX-1 signaling in cisplatin-induced cardiotoxicity

OBJECTIVE(S): Cisplatin (CP) is frequently used in various types of cancers. The cardiotoxic effects of this agent limit its usage. Our study seeks to investigate the protective effects of Irbesartan (IRB) on CP-induced cardiotoxicity. MATERIALS AND METHODS: The following four groups comprised thirt...

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Detalles Bibliográficos
Autores principales: Karatopuk, Dilek Ulusoy, Özkula, Songül, Aydoğdu, Esra, Büyükbayram, Halil İbrahim, Milletsever, Adem, Aksoy, Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598814/
https://www.ncbi.nlm.nih.gov/pubmed/37885998
http://dx.doi.org/10.22038/IJBMS.2023.70997.15422