Structural Insights into the Binding and Degradation Mechanisms of Protoporphyrin IX by the Translocator Protein TSPO

[Image: see text] The 18 kDa translocator protein (TSPO) has gained considerable attention as a clinical biomarker for neuroinflammation and a potential therapeutic target. However, the mechanisms by which TSPO associates with ligands, particularly the endogenous porphyrin ligand protoporphyrin IX (...

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Detalles Bibliográficos
Autores principales: Yeh, Pei-Shan, Li, Chieh-Chin, Lu, Yi-Shan, Chiang, Yun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598825/
https://www.ncbi.nlm.nih.gov/pubmed/37885593
http://dx.doi.org/10.1021/jacsau.3c00514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598825/
https://www.ncbi.nlm.nih.gov/pubmed/37885593
http://dx.doi.org/10.1021/jacsau.3c00514

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