Leishmania major-derived lipophosphoglycan influences the host’s early immune response by inducing platelet activation and DKK1 production via TLR1/2

BACKGROUND: Platelets are rapidly deployed to infection sites and respond to pathogenic molecules via pattern recognition receptors (TLR, NLRP). Dickkopf1 (DKK1) is a quintessential Wnt antagonist produced by a variety of cell types including platelets, endothelial cells, and is known to modulate pr...

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Detalles Bibliográficos
Autores principales: Ihedioha, Olivia C., Sivakoses, Anutr, Beverley, Stephen M., McMahon-Pratt, Diane, Bothwell, Alfred L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598878/
https://www.ncbi.nlm.nih.gov/pubmed/37885890
http://dx.doi.org/10.3389/fimmu.2023.1257046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598878/
https://www.ncbi.nlm.nih.gov/pubmed/37885890
http://dx.doi.org/10.3389/fimmu.2023.1257046

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