One episode of low intensity aerobic exercise prior to systemic AAV9 administration augments transgene delivery to the heart and skeletal muscle

INTRODUCTION: The promising potential of adeno-associated virus (AAV) gene delivery strategies to treat genetic disorders continues to grow with an additional three AAV-based therapies recently approved by the Food and Drug Administration and dozens of others currently under evaluation in clinical t...

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Detalles Bibliográficos
Autores principales: Pacak, Christina A., Suzuki-Hatano, Silveli, Khadir, Fatemeh, Daugherty, Audrey L., Sriramvenugopal, Mughil, Gosiker, Bennett J., Kang, Peter B., Cade, William Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598899/
https://www.ncbi.nlm.nih.gov/pubmed/37875924
http://dx.doi.org/10.1186/s12967-023-04626-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598899/
https://www.ncbi.nlm.nih.gov/pubmed/37875924
http://dx.doi.org/10.1186/s12967-023-04626-1

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