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Implementing patient derived organoids in functional precision medicine for patients with advanced colorectal cancer

BACKGROUND: Patient Derived Organoids (PDOs) emerged as the best technology to develop ex vivo tumor avatars. Whether drug testing on PDOs to identify efficient therapies will bring clinical utility by improving patient survival remains unclear. To test this hypothesis in the frame of clinical trial...

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Detalles Bibliográficos
Autores principales: Cartry, Jérôme, Bedja, Sabrina, Boilève, Alice, Mathieu, Jacques R. R., Gontran, Emilie, Annereau, Maxime, Job, Bastien, Mouawia, Ali, Mathias, Pierre, De Baère, Thierry, Italiano, Antoine, Besse, Benjamin, Sourrouille, Isabelle, Gelli, Maximiliano, Bani, Mohamed-Amine, Dartigues, Peggy, Hollebecque, Antoine, Smolenschi, Cristina, Ducreux, Michel, Malka, David, Jaulin, Fanny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598932/
https://www.ncbi.nlm.nih.gov/pubmed/37880806
http://dx.doi.org/10.1186/s13046-023-02853-4