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Global-scale GWAS associates a subset of SNPs with animal-adapted variants in M. tuberculosis complex

BACKGROUND: While Mycobacterium tuberculosis complex (MTBC) variants are clonal, variant tuberculosis is a human-adapted pathogen, and variant bovis infects many hosts. Despite nucleotide identity between MTBC variants exceeding 99.95%, it remains unclear what drives these differences. Markers of ad...

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Detalles Bibliográficos
Autores principales: Brenner, Evan P., Sreevatsan, Srinand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598944/
https://www.ncbi.nlm.nih.gov/pubmed/37875894
http://dx.doi.org/10.1186/s12920-023-01695-5